NIOSH approved for environments containing certain non-oil based particles. Use with 3M™ Respirators 5000 Series or 3M™ Cartridges 6000 Series, and 3M™ Filter Retainer 501. When properly fitted, use with appropriate cartridges for various applications including spray painting, petrochemical and chemical manufacturing, and pesticide spraying for concentrations up to 10 times the Permissible Exposure Limit (PEL) with half facepieces or 50 times PEL with full facepieces. Full facepieces must be quantitatively fit tested to claim assigned protection factor above 10 in negative pressure mode. Do not use for aerosols containing oil or in environments that are immediately dangerous to life or health (IDLH).