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Nalgene® conical bottom centrifuge bottles have molded-in graduations and are available in a variety of different plastics and closures to fit your lab's specific application. Conical bottom plastic centrifuge bottles have excellent chemical resistance and are designed for pelleting applications such as cell culture harvesting and protein biochemistry including ammonium sulfate precipitations. Excellent for use in refrigerated or non-refrigerated centrifuges. Before autoclaving just set closure on top of bottle without engaging the threads. For proper performance this bottle must be filled to at least 80% of the total capacity.