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This AxyVac™ microplate vacuum manifold system includes the manifold base, manifold top, middle support, plate support, block support, and waste reservoir. It is designed to accommodate a wide variety of different columns and SBS-format, 96- and 3-well filtering microplates for filtration-type sample purification. Features a single manifold for both column- and plate-based sample preps and has integrated controls for vacuum regulation. It is constructed of durable, long-lasting materials that offer exceptional resistance against breakage and chemical degradation.