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Wheaton® glass diagnostic bottles are manufactured from Wheaton 400 borosilicate glass which conforms to USP Type I requirements. Glass diagnostic bottles are a great alternative to serum bottles and vials. The are ideal for sample freeze drying and lyophilization. Wheaton® I-Loc™ diagnostic bottle screw cap closures are recommended. Screw cap closures with a thin flange stopper can also be used with these bottles. Borosilicate glass construction provides superior chemical resistance. Fully autoclavable for sterile applications.