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High Yield performace Flask (HYPERFlask®) cell culture vessel has 1720cm2 available growth area on a polystyrene gas permeable surface. It is made with USP Class VI materials and molded and assembled in a Certified Class 100,000 clean room. The vessel is surface treated with Corning® CellBIND® surface treatment for optimal cell attachment, and gamma irradiated for sterilization assurance. It has a 10-fold higher cell yield that increases productivity and capacity. It reduces processing time and incubator storage space by handling one flask compared to ten traditional 175sqcm flasks. Bar coded and compatible for use on cell culture automation platforms. Solid orange high density polyethylene cap with liner on a straight neck. Vessel is designed for filling with growth medium.